A Phase 1a/1b Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BGB-53038, a Pan-KRAS Inhibitor, as Monotherapy or in Combinations in Patients With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplifications
Latest Information Update: 08 May 2025
At a glance
- Drugs BGB 53038 (Primary) ; Cetuximab (Primary) ; Tislelizumab (Primary)
- Indications Colorectal cancer; Non-small cell lung cancer; Solid tumours
- Focus Adverse reactions; First in man; Therapeutic Use
- Sponsors BeOne Medicines
Most Recent Events
- 27 Feb 2025 According to BeiGene media release, data readout is anticipated in first half of 2025.
- 13 Dec 2024 Status changed from not yet recruiting to recruiting.
- 10 Sep 2024 New trial record