Trial Profile

A Phase 1, First-in-Human, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of XmAb657 in Healthy Participants and in Participants With Idiopathic Inflammatory Myopathy

Status: Not yet recruiting

Phase of Trial: Phase I

Latest Information Update: 20 Jan 2026

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At a glance

08 Jan 2026 According to a Xencor media release, the company plans to provide update on progress achieved in the Phase 1 study of XmAb657 in 2H26.
16 Dec 2025 Status changed from planning to not yet recruiting.
06 Aug 2025 According to a Xencor media release, company remain on-track to start a proof-of-concept study of XmAb657.

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