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Phase 2a basket study assessing ORX750 in patients with narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH).

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Trial Profile

Phase 2a basket study assessing ORX750 in patients with narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH).

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Dec 2024

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At a glance

  • Drugs ORX 750 (Primary)
  • Indications Idiopathic hypersomnia; Narcolepsy
  • Focus Therapeutic Use

    • Most Recent Events

    • 12 Nov 2024 According to Centessa Pharmaceuticals media release, this Phase 2a study of ORX750 is intended to accelerate overall timelines and inform future registrational studies.
    • 12 Nov 2024 According to Nxera Pharma media release, Centessa Pharmaceuticals has initiated a Phase 2a clinical study of ORX750 in patients with narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH). The achievement of this milestone will lead to a payment of USD 3.5 million to Nxera pursuant to its research collaboration with Centessa. This will be recognized as revenue in Q4 FY2024.
    • 12 Nov 2024 Status changed from planning to recruiting, according to Nxera Pharma media release.

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