Trial Profile

A Phase 2b/3, Randomized, Double-Blind Study to Investigate the Efficacy, Safety, and Tolerability of Ponsegromab (PF-06946860) Compared With Placebo Both With Background First-Line Chemotherapy in Adult Participants With Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma

Status: Recruiting

Phase of Trial: Phase II/III

Latest Information Update: 27 Oct 2025

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At a glance

14 Oct 2025 Planned End Date changed from 5 Nov 2029 to 23 Dec 2029.
14 Oct 2025 Planned primary completion date changed from 13 Dec 2027 to 30 Jan 2028.
14 Oct 2025 Planned initiation date (estimated date of first patient enrollment) changed from 29 Aug 2025 to 3 Oct 2025.

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