Trial Profile

A Phase 2b/3, Randomized, Double-Blind Study to Investigate the Efficacy, Safety, and Tolerability of Ponsegromab (PF-06946860) Compared With Placebo Both With Background First-Line Chemotherapy in Adult Participants With Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma

Status: Recruiting

Phase of Trial: Phase II/III

Latest Information Update: 31 Aug 2026

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At a glance

27 Apr 2026 Planned End Date changed from 23 Dec 2029 to 10 Dec 2029.
27 Apr 2026 Planned primary completion date changed from 30 Jan 2028 to 17 Jan 2028.
14 Oct 2025 Planned End Date changed from 5 Nov 2029 to 23 Dec 2029.

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