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A PHASE 2b/3, RANDOMIZED, DOUBLE-BLIND STUDY TO INVESTIGATE THE EFFICACY, SAFETY, AND TOLERABILITY OF PONSEGROMAB (PF-06946860) COMPARED WITH PLACEBO BOTH WITH BACKGROUND FIRST-LINE CHEMOTHERAPY IN ADULT PARTICIPANTS WITH CACHEXIA AND METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA

Trial Profile

A PHASE 2b/3, RANDOMIZED, DOUBLE-BLIND STUDY TO INVESTIGATE THE EFFICACY, SAFETY, AND TOLERABILITY OF PONSEGROMAB (PF-06946860) COMPARED WITH PLACEBO BOTH WITH BACKGROUND FIRST-LINE CHEMOTHERAPY IN ADULT PARTICIPANTS WITH CACHEXIA AND METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA

Status: Not yet recruiting
Phase of Trial: Phase II/III

Latest Information Update: 18 Jun 2025

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At a glance

  • Drugs Ponsegromab (Primary)
  • Indications Cachexia
  • Focus Registrational; Therapeutic Use
  • Sponsors Pfizer

Most Recent Events

  • 12 Jun 2025 Planned End Date changed from 7 Jan 2029 to 7 Jan 2030.
  • 12 Jun 2025 Planned primary completion date changed from 7 Jan 2029 to 6 Feb 2028.
  • 25 May 2025 Status changed from planning to not yet recruiting.

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