A Phase 2 Double-Blind Placebo-Controlled Single-Dose Study of Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of REGN7544, an NPR1 Antagonist Monoclonal Antibody, in Patients With Postural Orthostatic Tachycardia Syndrome
Latest Information Update: 13 Feb 2026
At a glance
- Drugs REGN-7544 (Primary)
- Indications Postural orthostatic tachycardia syndrome
- Focus Therapeutic Use
- Acronyms PINNACLE
- Sponsors Regeneron Pharmaceuticals
Most Recent Events
- 06 Feb 2026 Planned End Date changed from 21 Apr 2026 to 11 Jun 2026.
- 06 Feb 2026 Planned primary completion date changed from 28 Jan 2026 to 20 Mar 2026.
- 22 Nov 2024 Status changed from not yet recruiting to recruiting.