A Randomized, Double-blind, Parallel-group Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of JPB898 (proposed Nivolumab Biosimilar) and US-licensed and EU-authorized Opdivo in Combination with Yervoy in Participants with Untreated Advanced (unresectable/metastatic) Melanoma
Latest Information Update: 10 Mar 2026
At a glance
- Drugs Nivolumab (Primary) ; Ipilimumab; Nivolumab
- Indications Malignant melanoma
- Focus Pharmacokinetics; Registrational; Therapeutic Use
- Sponsors HEXAL; Sandoz
Most Recent Events
- 24 Feb 2026 Status changed from suspended to discontinued.
- 07 Aug 2025 Planned End Date changed from 31 Jul 2027 to 1 Feb 2026.
- 07 Aug 2025 Planned primary completion date changed from 31 Jul 2027 to 1 Feb 2026.