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An Open-Label, Phase 1 Study to Characterize the Effects of a Strong Cytochrome P450 3A4 Inducer on the Pharmacokinetics of Bomedemstat in Healthy Adult Participants

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An Open-Label, Phase 1 Study to Characterize the Effects of a Strong Cytochrome P450 3A4 Inducer on the Pharmacokinetics of Bomedemstat in Healthy Adult Participants

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 29 Nov 2024

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At a glance

  • Drugs Bomedemstat (Primary) ; Carbamazepine
  • Indications Acute myeloid leukaemia; Essential thrombocythaemia; Myelodysplastic syndromes; Myelofibrosis; Polycythaemia vera; Small cell lung cancer
  • Focus Pharmacokinetics
  • Sponsors Merck Sharp & Dohme

    • Most Recent Events

    • 27 Nov 2024 Planned End Date changed from 25 Nov 2024 to 16 Feb 2025.
    • 27 Nov 2024 Planned primary completion date changed from 25 Nov 2024 to 3 Feb 2025.
    • 02 Oct 2024 Status changed from not yet recruiting to recruiting.

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