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An Open-Label, Phase 1 Study to Characterize the Effects of a Strong Cytochrome P450 3A4 Inducer on the Pharmacokinetics of Bomedemstat in Healthy Adult Participants

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Trial Profile

An Open-Label, Phase 1 Study to Characterize the Effects of a Strong Cytochrome P450 3A4 Inducer on the Pharmacokinetics of Bomedemstat in Healthy Adult Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 Mar 2025

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At a glance

  • Drugs Bomedemstat (Primary) ; Carbamazepine
  • Indications Acute myeloid leukaemia; Essential thrombocythaemia; Myelodysplastic syndromes; Myelofibrosis; Polycythaemia vera; Small cell lung cancer
  • Focus Pharmacokinetics
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 18 Mar 2025 Status changed from active, no longer recruiting to completed.
  • 04 Mar 2025 Planned End Date changed from 16 Feb 2025 to 3 Mar 2025.
  • 17 Jan 2025 Status changed from recruiting to active, no longer recruiting.

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