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A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Induction Therapy With RO7790121 in Patients With Moderately to Severely Active Ulcerative Colitis

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Trial Profile

A Phase III, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Induction Therapy With RO7790121 in Patients With Moderately to Severely Active Ulcerative Colitis

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 24 Apr 2026

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At a glance

  • Drugs Afimkibart (Primary) ; Afimkibart (Primary)
  • Indications Ulcerative colitis
  • Focus Registrational; Therapeutic Use
  • Acronyms Ametrine-2
  • Sponsors Roche

Most Recent Events

  • 02 Apr 2026 Planned End Date changed from 30 Dec 2029 to 30 Jan 2031.
  • 02 Apr 2026 Planned primary completion date changed from 30 Jun 2027 to 30 Jan 2027.
  • 05 Nov 2024 Planned initiation date changed from 30 Oct 2024 to 31 Dec 2024.

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