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A Phase Ib, Double-blind, Placebo-controlled, Randomised Trial Investigating the Effect of AZD3427 on Renal Perfusion in HFrEF Patients With Renal Impairment Using Positron Emission Tomography (PET)

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Trial Profile

A Phase Ib, Double-blind, Placebo-controlled, Randomised Trial Investigating the Effect of AZD3427 on Renal Perfusion in HFrEF Patients With Renal Impairment Using Positron Emission Tomography (PET)

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 14 Oct 2025

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At a glance

  • Drugs AZD 3427 (Primary) ; Dopamine
  • Indications Heart failure
  • Focus Therapeutic Use
  • Acronyms Re-PERFUS
  • Sponsors AstraZeneca

Most Recent Events

  • 24 Sep 2025 Status changed from recruiting to discontinued.
  • 15 Aug 2025 Planned End Date changed from 5 Sep 2025 to 24 Oct 2025.
  • 15 Aug 2025 Planned primary completion date changed from 5 Sep 2025 to 24 Oct 2025.

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