Trial Profile

Effect of a Single Dose of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery: a Randomized Controlled Trial

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 10 Dec 2025

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At a glance

Drugs Esketamine (Primary)
Indications Anxiety; Depression
Focus Therapeutic Use

Most Recent Events

01 Dec 2025 Primary endpoint (Perioperative anxiety and depression at Post-operative day 7 (POD 7)) has been met, according to the results presented in the Pharmacological Research.
01 Dec 2025 Results assessing the efficacy of esketamine on postoperative depression and anxiety in patients undergoing cardiac valve surgery, presented in the Pharmacological Research.
25 Nov 2025 Status changed from recruiting to completed.

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