Trial Profile

A Randomized, Multicenter, Controlled Study of Irinotecan Hydrochloride Liposome Injection (II) Combined with Fluorouracil, Folinic Acid, Vermofenib and Cetuximab in First-line Treatment of BRAFV600E Mutated Advanced Colorectal Cancer

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 24 Jun 2025

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At a glance

Drugs Cetuximab (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Vemurafenib (Primary) ; Bevacizumab
Indications Adenocarcinoma; Colorectal cancer
Focus Therapeutic Use
Acronyms IMPROVEMENT-2

25 Jan 2025 Trial design presented at the 2025 Gastrointestinal Cancers Symposium
01 Oct 2024 New trial record

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