A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamic Effects of REGN7544, an Antagonist Monoclonal Antibody to NPR1, in Patients With Sepsis-Induced Hypotension
Latest Information Update: 08 Jun 2026
At a glance
- Drugs Baloncibart (Primary)
- Indications Sepsis
- Focus Therapeutic Use
- Acronyms ESTELLA
- Sponsors Regeneron Pharmaceuticals
Most Recent Events
- 20 May 2026 Status changed from active, no longer recruiting to completed.
- 27 Apr 2025 Planned initiation date (estimated date of first patient enrollment) changed from 24 Mar 2025 to 30 Apr 2025.
- 13 Mar 2025 Planned End Date changed from 19 Sep 2026 to 19 Oct 2026.