A Phase I/IIa, Open-label, Multi-centre Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AZD0022 Monotherapy and in Combination With Anti-cancer Agents in Participants With Tumours Harbouring a KRASG12D Mutation (ALAFOSS-01)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 04 Nov 2024

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At a glance

Drugs AZD 0022 (Primary) ; Cetuximab (Primary)
Indications Adenocarcinoma; Colorectal cancer; Ductal carcinoma; Non-small cell lung cancer; Pancreatic cancer; Solid tumours
Focus Adverse reactions; First in man; Therapeutic Use
Acronyms ALAFOSS-01
Sponsors AstraZeneca

Most Recent Events

30 Oct 2024 Planned End Date changed from 20 Jan 2028 to 3 Feb 2028.
30 Oct 2024 Status changed from not yet recruiting to recruiting.
01 Oct 2024 New trial record

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