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A Phase 2b, Multi-Center, Randomized, Placebo-Controlled Double-Blind Study to Investigate the Safety and Efficacy of Once-Weekly MET097 in Participants with Obesity and Overweight (VESPER-1)

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Trial Profile

A Phase 2b, Multi-Center, Randomized, Placebo-Controlled Double-Blind Study to Investigate the Safety and Efficacy of Once-Weekly MET097 in Participants with Obesity and Overweight (VESPER-1)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Aug 2025

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At a glance

  • Drugs MET 097 (Primary)
  • Indications Obesity
  • Focus Therapeutic Use
  • Acronyms VESPER-1
  • Sponsors Metsera

Most Recent Events

  • 28 Jul 2025 According to a Metsera media release, topline data expected in Sep 2025.
  • 21 Feb 2025 Planned End Date changed from 1 Sep 2025 to 1 Oct 2025.
  • 21 Feb 2025 Planned primary completion date changed from 1 Jun 2025 to 1 Aug 2025.

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