Trial Profile

An Open-label, Multi-center, Phase 1/2 Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Participants With Relapsing Multiple Sclerosis With Breakthrough Disease Activity During Previous Treatment With a Highly Efficacious Therapy

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 04 Sep 2026

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At a glance

Drugs Rapcabtagene autoleucel (Primary) ; Cyclophosphamide; Fludarabine; Tocilizumab
Indications Multiple sclerosis
Focus Adverse reactions
Sponsors Novartis Pharmaceuticals

02 Sep 2026 Status changed from recruiting to active, no longer recruiting.
04 Aug 2026 Planned End Date changed from 1 Oct 2030 to 7 Aug 2030.
04 Aug 2026 Planned primary completion date changed from 1 Oct 2030 to 7 Aug 2030.

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