Trial Profile

A Randomized, Controlled, Open-label, Multicenter Phase III Clinical Study of Anti CTLA-4 Antibody SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab Combined With Bevacizumab for the First-line Treatment of Advanced Hepatocellular Carcinoma

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 26 May 2026

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At a glance

Drugs Adebrelimab (Primary) ; Bevacizumab (Primary) ; SHR 8068 (Primary) ; Sintilimab (Primary)
Indications Liver cancer
Focus Therapeutic Use
Sponsors Suzhou Suncadia Biopharmaceuticals

04 May 2026 Planned End Date changed from 31 Dec 2030 to 1 Dec 2030.
04 May 2026 Planned primary completion date changed from 31 Mar 2026 to 1 Sep 2026.
15 May 2025 Planned number of patients changed from 560 to 590.

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