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DT2216 in Combination With Irinotecan for Children, Adolescents and Young Adults With Relapsed or Refractory Solid Tumors: A Phase I Study With Phase II Feasibility Cohort for Fibrolamellar Carcinoma

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Trial Profile

DT2216 in Combination With Irinotecan for Children, Adolescents and Young Adults With Relapsed or Refractory Solid Tumors: A Phase I Study With Phase II Feasibility Cohort for Fibrolamellar Carcinoma

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 Jun 2025

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At a glance

  • Drugs DT 2216 (Primary) ; Irinotecan (Primary)
  • Indications Carcinoma; Solid tumours
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use

Most Recent Events

  • 05 Jun 2025 Planned initiation date (estimated date of first participant enrollment) changed from 20 Jun 2025 to 21 Feb 2026.
  • 05 Jun 2025 Status changed from not yet recruiting to recruiting.
  • 26 Mar 2025 Planned initiation date changed from 20 Mar 2025 to 20 Jun 2025.

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