Trial Profile

A Pilot Safety and Feasibility Study of Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 01 Apr 2026

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At a glance

Drugs Ciltacabtagene autoleucel (Primary) ; Cyclophosphamide (Primary) ; Fludarabine
Indications Multiple myeloma
Focus Adverse reactions

11 Mar 2026 Planned number of patients changed from 12 to 16.
11 Mar 2026 Planned End Date changed from 31 Mar 2027 to 31 May 2028.
11 Mar 2026 Planned primary completion date changed from 30 Apr 2026 to 30 Jun 2027.

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