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Daratumumab Combined With Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis Patients With Translocation (11;14): A Multicenter Phase 2 Study

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Trial Profile

Daratumumab Combined With Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis Patients With Translocation (11;14): A Multicenter Phase 2 Study

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Aug 2026

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At a glance

  • Drugs Daratumumab (Primary) ; Daratumumab (Primary) ; Dexamethasone (Primary) ; Venetoclax (Primary)
  • Indications Amyloid light-chain amyloidosis
  • Focus Therapeutic Use

Most Recent Events

  • 28 Jul 2026 Planned End Date changed from 14 Oct 2026 to 14 Mar 2027.
  • 28 Jul 2026 Status changed from recruiting to active, no longer recruiting.
  • 22 Jan 2025 Status changed from not yet recruiting to recruiting.

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