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Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART): Adaptive Clinical Treatment (ACT)

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Trial Profile

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART): Adaptive Clinical Treatment (ACT)

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 23 Dec 2024

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At a glance

  • Drugs Abemaciclib (Primary) ; Carboplatin (Primary) ; Doxorubicin (Primary) ; Exemestane (Primary) ; Fulvestrant (Primary) ; Gefitinib (Primary) ; Gemcitabine (Primary) ; Letrozole (Primary) ; Olaparib (Primary) ; Osimertinib (Primary) ; Pemetrexed (Primary) ; Tamoxifen (Primary) ; Temozolomide (Primary)
  • Indications Advanced breast cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Sarcoma
  • Focus Therapeutic Use
  • Acronyms SMMART-ACT

    • Most Recent Events

    • 18 Dec 2024 Planned number of patients changed from 38 to 30.
    • 18 Dec 2024 Planned initiation date changed from 1 Jan 2025 to 1 Feb 2025.
    • 14 Oct 2024 New trial record

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