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A First-in-human, Phase 1/2, Multicenter, Open-label, Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of ADCE-D01, a Humanized Anti-human UPARAP Antibody Linked to a Topoisomerase I Inhibitor, in Patients with Metastatic And/or Unresectable Soft Tissue Sarcoma

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Trial Profile

A First-in-human, Phase 1/2, Multicenter, Open-label, Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of ADCE-D01, a Humanized Anti-human UPARAP Antibody Linked to a Topoisomerase I Inhibitor, in Patients with Metastatic And/or Unresectable Soft Tissue Sarcoma

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 05 Feb 2025

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At a glance

  • Drugs ADCE D01 (Primary)
  • Indications Soft tissue sarcoma
  • Focus Adverse reactions; First in man
  • Acronyms ADCElerate-01
  • Sponsors ADCendo

    • Most Recent Events

    • 14 Oct 2024 New trial record
    • 08 Oct 2024 According to Adcendo Media release, Patrick Schoffski is the Principal investigator of the ADCElerate-01 trial.
    • 08 Oct 2024 According to Adcendo Media release, company announces US FDA Clearance of IND Application for Phase I/II First-in-Human ADCElerate-01 Trial of ADCE-D01 (uPARAP Receptor Targeting ADC) Trial in Patients with Metastatic and/or Unresectable Soft Tissue Sarcoma (STS)

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