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An Open-label, Randomized, Three-arm Study Evaluating the Potential of BMS-984923 to Alter the Systemic Exposure of Three Orally Administered Probe Substrates in Healthy Adult Participants

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Trial Profile

An Open-label, Randomized, Three-arm Study Evaluating the Potential of BMS-984923 to Alter the Systemic Exposure of Three Orally Administered Probe Substrates in Healthy Adult Participants

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Nov 2024

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At a glance

  • Drugs ALX-001 (Primary) ; Caffeine; Dextromethorphan; Midazolam
  • Indications Alzheimer's disease; Parkinson's disease
  • Focus Pharmacokinetics
  • Sponsors Allyx Therapeutics
  • Most Recent Events

    • 20 Nov 2024 Planned primary completion date changed from 1 Mar 2025 to 1 Jan 2025.
    • 20 Nov 2024 Status changed from not yet recruiting to active, no longer recruiting.
    • 15 Oct 2024 According to an Allyx Therapeutics meida release, company has been awarded a $3.3 million grant from the National Institutes of Health as part of its Small Business Innovation Research Commercial Readiness Pilot program. This funding will support further investigation ALX-001 and company intends to utilize this Commercial Readiness Pilot funding to support Phase I clinical pharmacokinetic drug-drug interaction study.

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