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A Randomized, Double-Blinded, Controlled Trial Evaluating Recombinant Human Platelet-Derived Growth Factor B (rhPDGF-BB)-Enhanced Wound Matrix in the Reconstruction of Full-Thickness Head or Neck Defects Following Skin Cancer Excision

Trial Profile

A Randomized, Double-Blinded, Controlled Trial Evaluating Recombinant Human Platelet-Derived Growth Factor B (rhPDGF-BB)-Enhanced Wound Matrix in the Reconstruction of Full-Thickness Head or Neck Defects Following Skin Cancer Excision

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Aug 2026

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At a glance

  • Drugs GEM 21S (Primary)
  • Indications Bone disorders
  • Focus Therapeutic Use

Most Recent Events

  • 18 Aug 2026 According to Lynch Regenerative Medicine media release, company announced the completion of enrollment in this trial. Patients are followed over the studys eight-week assessment period, after which data will be analyzed.The use of rhPDGF-BB being evaluated in this study is investigational and has not been approved by the U.S. Food and Drug Administration for this indication. The study remains ongoing, and no conclusions regarding safety or effectiveness can be drawn until the study is completed.
  • 20 Jul 2026 Status changed from recruiting to completed.
  • 23 Mar 2026 Planned End Date changed from 1 May 2026 to 1 Jun 2026.

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