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A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Empasiprubart Versus Intravenous Immunoglobulin in Adults With Multifocal Motor Neuropathy

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Trial Profile

A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Empasiprubart Versus Intravenous Immunoglobulin in Adults With Multifocal Motor Neuropathy

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 09 Mar 2026

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At a glance

  • Drugs Empasiprubart (Primary) ; Immunoglobulins
  • Indications Multifocal motor neuropathy
  • Focus Registrational; Therapeutic Use
  • Acronyms EMPASSION
  • Sponsors argenx

Most Recent Events

  • 27 Feb 2026 According to an argenx media releease, Topline results from EMPASSION study (MMN) expected in fourth quarter of 2026
  • 24 Aug 2025 Planned number of patients changed from 100 to 115.
  • 13 Jan 2025 According to an argenx SE media releease, registrational EMPASSION study ongoing in MMN evaluating empasiprubart head-to-head versus IVIg, topline results expected in second half of 2026.

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