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Phase I Trial of MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Trial Profile

Phase I Trial of MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 May 2025

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At a glance

  • Drugs Zunsemetinib (Primary) ; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Adenocarcinoma; Adenosquamous carcinoma; Neuroendocrine carcinoma; Pancreatic ductal carcinoma
  • Focus Adverse reactions

Most Recent Events

  • 23 May 2025 Status changed from not yet recruiting to recruiting.
  • 28 Apr 2025 Planned End Date changed from 31 Mar 2030 to 31 May 2030.
  • 23 Apr 2025 Planned primary completion date changed from 30 Apr 2027 to 30 Jun 2027.

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