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Open-label, cohort-sequential dose-escalation and dose-confirmation Phase 1/2 clinical trial to evaluate the safety and efficacy of domatinostat in combination with sirolimus in adolescents and adults with advanced sarcoma and osteosarcoma

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Open-label, cohort-sequential dose-escalation and dose-confirmation Phase 1/2 clinical trial to evaluate the safety and efficacy of domatinostat in combination with sirolimus in adolescents and adults with advanced sarcoma and osteosarcoma

Status: Planning
Phase of Trial: Phase I/II

Latest Information Update: 24 Oct 2024

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At a glance

  • Drugs Domatinostat/Sirolimus (Primary)
  • Indications Osteosarcoma; Sarcoma
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 24 Oct 2024 New trial record
    • 24 Sep 2024 According to Vuja De Sciences media release, company announced that the U.S. Food and Drug Administration (FDA) has cleared the company's Investigational New Drug (IND) application for VUJ-100 for the treatment of relapsed, refractory sarcoma and osteosarcoma on Sep 11, 2024.

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