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A Phase 2, Randomized, Double-blind, Placebo-controlled Parallel Group Study of VHB937 in Amyotrophic Lateral Sclerosis (ALS) Over 40 Weeks Followed by an Open Label Extension (ASTRALS)

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Trial Profile

A Phase 2, Randomized, Double-blind, Placebo-controlled Parallel Group Study of VHB937 in Amyotrophic Lateral Sclerosis (ALS) Over 40 Weeks Followed by an Open Label Extension (ASTRALS)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 17 Nov 2025

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At a glance

  • Drugs VHB 937 (Primary)
  • Indications Amyotrophic lateral sclerosis
  • Focus Therapeutic Use
  • Acronyms ASTRALS
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 12 Nov 2025 Planned End Date changed from 20 Jun 2028 to 7 Jul 2028.
  • 12 Nov 2025 Planned primary completion date changed from 29 Jan 2027 to 21 Sep 2026.
  • 27 Oct 2025 Status changed from recruiting to active, no longer recruiting.

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