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A Phase 1/2 Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of ABO-101 in Participants With Primary Hyperoxaluria Type 1 (PH1)

Trial Profile

A Phase 1/2 Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of ABO-101 in Participants With Primary Hyperoxaluria Type 1 (PH1)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 09 Oct 2025

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At a glance

  • Drugs ABO 101 Arbor Biotechnologies (Primary)
  • Indications Hyperoxaluria
  • Focus Adverse reactions
  • Acronyms RedePHine
  • Sponsors Arbor Biotechnologies

Most Recent Events

  • 06 Oct 2025 According to a Chiesi media release, Arbor and Chiesi will collaborate on the ongoing Phase 1/2 redePHine (NCT06839235) clinical study of ABO-101 in PH1.
  • 30 Jul 2025 According to an Arbor Biotechnologies media release, dose escalation ongoing with enrollment at Mayo Clinic in the US and plans to open additional sites in the UK and EU in Q3 of this year.
  • 30 Jul 2025 According to an Arbor Biotechnologies media release, first patient has been dosed in this trial.

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