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An Open-Label Phase 2 Study to Evaluate the Safety, Tolerability, and Effect on Albuminuria of MZE829 in Adults with Proteinuric Chronic Kidney Disease and the APOL1 High Risk Genotype

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Trial Profile

An Open-Label Phase 2 Study to Evaluate the Safety, Tolerability, and Effect on Albuminuria of MZE829 in Adults with Proteinuric Chronic Kidney Disease and the APOL1 High Risk Genotype

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 21 Feb 2025

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At a glance

  • Drugs MZE-829 (Primary)
  • Indications Renal failure
  • Focus Adverse reactions; Proof of concept
  • Acronyms HORIZON
  • Sponsors Maze Therapeutics

Most Recent Events

  • 07 Feb 2025 According to Maze Therapeutics media release, proof of concept interim data readout expected in the first quarter of 2026.
  • 07 Feb 2025 According to Maze Therapeutics media release, first patient has been dosed in this trial.
  • 07 Feb 2025 Status changed from planning to recruiting, according to a Maze Therapeutics media release.

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