Trial Profile

Phase 1 Study of a SOS1 Inhibitor, BAY 3498264, in Combination in Participants With Advanced KRASG12C-mutated Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 25 Sep 2026

Price :

$35 ^*

Note:

Adis is an information provider.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

Drugs BAY-3498264 (Primary) ; Sotorasib (Primary)
Indications Solid tumours
Focus Adverse reactions; First in man; Pharmacokinetics
Acronyms 22676
Sponsors Bayer

Most Recent Events

26 Aug 2026 Planned End Date changed from 30 Jul 2027 to 6 Sep 2027.
26 Aug 2026 Planned primary completion date changed from 11 Jan 2027 to 26 Apr 2027.
03 Aug 2026 Planned End Date changed from 15 Jun 2027 to 30 Jul 2027.

You need to be a logged in or subscribed to view this content

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com