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A Phase 1/2a, Randomized, Double-blind, Placebo-controlled Study of Ascending Doses of WVE-007 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Adults Living With Overweight or Obesity

Trial Profile

A Phase 1/2a, Randomized, Double-blind, Placebo-controlled Study of Ascending Doses of WVE-007 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Adults Living With Overweight or Obesity

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Aug 2026

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At a glance

  • Drugs WVE 007 (Primary)
  • Indications Obesity; Overweight
  • Focus Adverse reactions; First in man; Proof of concept
  • Acronyms INLIGHT
  • Sponsors WaVe life Sciences

Most Recent Events

  • 30 Jul 2026 According to a Wave Life Sciences media release, dosing is underway in the Phase 2a multidose portion of the INLIGHT trial.
  • 30 Jul 2026 According to a Wave Life Sciences media release, an additional data from the INLIGHT trial, including data from the 600 mg Phase 1 SAD cohort, are expected in the second half of 2026.
  • 24 Jun 2026 According to a Wave Life Sciences media release, company announced it has initiated the Phase 2a multidose portion of this trial. The Phase 2a portion of the INLIGHT trial is expected to enroll participants across the U.S. and Europe.

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