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A Phase 1/2a, Randomized, Double-blind, Placebo-controlled Study of Ascending Doses of WVE-007 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Adults Living With Overweight or Obesity

Trial Profile

A Phase 1/2a, Randomized, Double-blind, Placebo-controlled Study of Ascending Doses of WVE-007 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Adults Living With Overweight or Obesity

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 01 Jul 2026

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At a glance

  • Drugs WVE 007 (Primary)
  • Indications Obesity; Overweight
  • Focus Adverse reactions; First in man; Proof of concept
  • Acronyms INLIGHT
  • Sponsors WaVe life Sciences

Most Recent Events

  • 24 Jun 2026 According to a Wave Life Sciences media release, company announced it has initiated the Phase 2a multidose portion of this trial. The Phase 2a portion of the INLIGHT trial is expected to enroll participants across the U.S. and Europe.
  • 02 Jun 2026 Planned number of patients changed from 136 to 296.
  • 02 Jun 2026 Planned End Date changed from 1 Oct 2026 to 1 Dec 2027.

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