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A Phase 1, Randomized, Double-blind, Placebo-controlled Study of Ascending Doses of WVE-007 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Adults Living with Overweight or Obesity

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Trial Profile

A Phase 1, Randomized, Double-blind, Placebo-controlled Study of Ascending Doses of WVE-007 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Adults Living with Overweight or Obesity

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 18 May 2025

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At a glance

  • Drugs WVE 007 (Primary)
  • Indications Obesity; Overweight
  • Focus Adverse reactions; First in man; Proof of concept
  • Acronyms INLIGHT
  • Sponsors WaVe life Sciences

Most Recent Events

  • 08 May 2025 According to a Wave Life Sciences media release, dosing complete in the first two cohorts of this trial in obesity and expects to deliver clinical data in second half of 2025, including safety, tolerability and biomarkers reflective of healthy weight loss.
  • 04 Mar 2025 According to a Wave Life Sciences media release, company expects to deliver clinical data from INLIGHT in the second half of 2025, including safety, tolerability and biomarkers reflective of healthy weight loss.
  • 04 Mar 2025 According to a Wave Life Sciences media release, company announced that it has completed enrollment in the first single dose cohort.

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