Trial Profile

A First-in-human, Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Anti-tumor Activity of SYN818, a DNA Polymerase Theta (POLQ) Inhibitor Alone in Patients with Locally Advanced or Metastatic Solid Tumors

Status: Not yet recruiting

Phase of Trial: Phase I

Latest Information Update: 05 Jun 2025

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At a glance

30 Apr 2025 Results assessing SYN818 in solid tumor patients presented at the 116th Annual Meeting of the American Association for Cancer Research.
05 Nov 2024 New trial record

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