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A First-in-human, Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Anti-tumor Activity of SYN818, a DNA Polymerase Theta (POLQ) Inhibitor Alone in Patients with Locally Advanced or Metastatic Solid Tumors

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A First-in-human, Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Anti-tumor Activity of SYN818, a DNA Polymerase Theta (POLQ) Inhibitor Alone in Patients with Locally Advanced or Metastatic Solid Tumors

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2024

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At a glance

  • Drugs SYN 818 (Primary)
  • Indications Breast cancer; Ovarian cancer; Prostate cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors SynRx Therapeutics

    • Most Recent Events

    • 05 Nov 2024 New trial record

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