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A Phase 1 Open-label, Non-randomized, Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

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Trial Profile

A Phase 1 Open-label, Non-randomized, Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Nov 2025

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At a glance

  • Drugs Poly ICLC (Primary)
  • Indications HIV infections
  • Focus Adverse reactions; Pharmacodynamics

Most Recent Events

  • 16 Sep 2025 Status changed from not yet recruiting to recruiting.
  • 05 Jun 2025 Planned initiation date changed from 23 May 2025 to 1 Dec 2025.
  • 27 Mar 2025 Planned initiation date changed from 4 Feb 2025 to 23 May 2025.

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