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A Phase 1 Open-label, Non-randomized, Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

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Trial Profile

A Phase 1 Open-label, Non-randomized, Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 23 Sep 2026

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At a glance

  • Drugs Poly ICLC (Primary)
  • Indications HIV infections
  • Focus Adverse reactions; Pharmacodynamics

Most Recent Events

  • 18 Sep 2026 Planned End Date changed from 4 May 2027 to 30 Nov 2027.
  • 18 Sep 2026 Planned primary completion date changed from 27 Jul 2026 to 30 Nov 2027.
  • 16 Sep 2025 Status changed from not yet recruiting to recruiting.

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