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A Phase 1, Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of ALN-AGT01 RVR in Adult Healthy Volunteers

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Trial Profile

A Phase 1, Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of ALN-AGT01 RVR in Adult Healthy Volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 26 Sep 2025

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At a glance

  • Drugs Zilebesiran (Primary)
  • Indications Hypertension
  • Focus Adverse reactions
  • Sponsors Alnylam Pharmaceuticals

Most Recent Events

  • 19 Sep 2025 Status changed from active, no longer recruiting to completed.
  • 26 Aug 2025 Status changed from recruiting to active, no longer recruiting.
  • 12 Dec 2024 Planned primary completion date changed from 5 Aug 2025 to 8 Sep 2025.

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