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A Phase I, Randomized, Double-Blind, Placebo-Controlled, Multi-Centre Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease

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Trial Profile

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Multi-Centre Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Jul 2026

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At a glance

  • Drugs Berzanoflast (Primary)
  • Indications Cardiovascular disorders; Ischaemic stroke; Myocardial infarction; Renal failure
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors AstraZeneca; AstraZeneca AB

Most Recent Events

  • 25 Nov 2025 Status changed from active, no longer recruiting to completed.
  • 10 Oct 2025 Status changed from recruiting to active, no longer recruiting.
  • 24 Aug 2025 Planned End Date changed from 8 Aug 2025 to 27 Oct 2025.

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