Trial Profile

A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of SPY002-091 in Healthy Participants

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 28 Aug 2026

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At a glance

Drugs SPY 002 (Primary)
Indications Inflammatory bowel diseases
Focus Adverse reactions; First in man
Sponsors Spyre Therapeutics

Most Recent Events

25 Aug 2026 Status changed from active, no longer recruiting to completed.
12 Jun 2026 Planned End Date changed from 22 Jun 2026 to 19 Aug 2026.
12 Jun 2026 Planned primary completion date changed from 18 Feb 2026 to 19 Aug 2026.

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