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A Multicenter, Open-label, Non-comparative, Single-arm, Phase II Trial of Datopotamab Deruxtecan for Non-small Cell Lung Cancer Patients with Active Brain Metastases (The TUXEDO-5 Study)

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Trial Profile

A Multicenter, Open-label, Non-comparative, Single-arm, Phase II Trial of Datopotamab Deruxtecan for Non-small Cell Lung Cancer Patients with Active Brain Metastases (The TUXEDO-5 Study)

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 25 Aug 2025

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At a glance

  • Drugs Datopotamab deruxtecan (Primary)
  • Indications Brain metastases; Cancer metastases; Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms TUXEDO-5

Most Recent Events

  • 08 Aug 2025 Planned initiation date changed from 1 Apr 2025 to 1 Jun 2025.
  • 08 Aug 2025 Status changed from not yet recruiting to withdrawn prior to enrolment.
  • 12 Nov 2024 New trial record

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