Trial Profile

A Phase 2 Study of Avutometinib (VS-6766, a Dual RAF/MEK Inhibitor) In Combination With Defactinib (FAK Inhibitor) in Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) in Japanese Patients

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 02 Mar 2026

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At a glance

04 Feb 2026 Results presented in the Verastem Oncology media release.
17 Dec 2025 Status changed from recruiting to active, no longer recruiting.
23 Jan 2025 According to a Verastem Oncology media release, Company to report initial data from the RAMP 201J Phase 2 clinical trial being conducted in Japan with the Japanese Gynecologic Oncology Group (JGOG) evaluating the safety and efficacy of avutometinib in combination with defactinib for recurrent LGSOC in H2 2025.

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