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A Phase 2 Study of Avutometinib (VS-6766, a Dual RAF/MEK Inhibitor) in Combination with Defactinib (FAK Inhibitor) in Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) in Japanese Patients

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Trial Profile

A Phase 2 Study of Avutometinib (VS-6766, a Dual RAF/MEK Inhibitor) in Combination with Defactinib (FAK Inhibitor) in Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) in Japanese Patients

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 19 Feb 2025

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At a glance

  • Drugs Avutometinib (Primary) ; Defactinib (Primary)
  • Indications Ovarian cancer; Peritoneal cancer
  • Focus Therapeutic Use
  • Acronyms RAMP201J
  • Sponsors Verastem Oncology

Most Recent Events

  • 23 Jan 2025 According to a Verastem Oncology media release, Company to report initial data from the RAMP 201J Phase 2 clinical trial being conducted in Japan with the Japanese Gynecologic Oncology Group (JGOG) evaluating the safety and efficacy of avutometinib in combination with defactinib for recurrent LGSOC in H2 2025.
  • 14 Nov 2024 New trial record

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