Trial Profile

A Phase 2, Open-Label Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DISC-3405 in Participants With Polycythemia Vera (PV)

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 16 Dec 2025

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At a glance

06 Dec 2025 According to Disc Medicine media release, company will present a poster on the design of our ongoing Phase 2 trial of DISC-3405 in polycythemia vera on Saturday, December 6, 5:30 pm to 7:30pm EST.
03 Nov 2025 According to a Disc Medicine media release, the company expect to share an initial readout for this trial, in 2026.
20 Oct 2025 According to a Mabwell (Shanghai) Bioscience media release, the company aims to establish Phase 2 proof-of-concept for DISC-3405 in PV and support its potential advancement into later-stage development. Topline data from the ongoing Phase 2 PV study are expected in 2026.

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