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Phase I/II study of TNG456 in glioblastoma, NSCLC and select other solid tumors as a monotherapy and in combination with the brain-penetrant CDK4/6 inhibitor abemaciclib (Lilly)

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Trial Profile

Phase I/II study of TNG456 in glioblastoma, NSCLC and select other solid tumors as a monotherapy and in combination with the brain-penetrant CDK4/6 inhibitor abemaciclib (Lilly)

Status: Planning
Phase of Trial: Phase I/II

Latest Information Update: 17 Nov 2024

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At a glance

  • Drugs Abemaciclib (Primary) ; TNG 456 (Primary)
  • Indications Glioblastoma; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 17 Nov 2024 New trial record
    • 06 Nov 2024 According to Tango Therapeutics media release, the Company plans to begin enrolling patients in the TNG456 phase 1/2 study in 1H 2025.

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