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A study of TNG462 combinations with two RAS(ON) inhibitors – RAS(ON) multi-selective inhibitor, RMC-6236, and RAS(ON) G12D-selective inhibitor, RMC-9805 (Revolution Medicines) – osimertinib (AstraZeneca) and pembrolizumab (Merck)

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Trial Profile

A study of TNG462 combinations with two RAS(ON) inhibitors – RAS(ON) multi-selective inhibitor, RMC-6236, and RAS(ON) G12D-selective inhibitor, RMC-9805 (Revolution Medicines) – osimertinib (AstraZeneca) and pembrolizumab (Merck)

Status: Planning
Phase of Trial: Phase II

Latest Information Update: 17 Nov 2024

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At a glance

  • Drugs Osimertinib (Primary) ; Pembrolizumab (Primary) ; RMC-6236 (Primary) ; RMC-9805 (Primary) ; TNG 462 (Primary)
  • Indications Cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 17 Nov 2024 New trial record
    • 06 Nov 2024 According to Tango Therapeutics media release, enrollment planned to start in 1H 2025.

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