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A Phase 1 Study Assessing Safety, Tolerability, Pharmacokinetics and Physiological Response (Pain Tolerance) to Single and Multiple Ascending Doses of FZ008-145 in Healthy Subjects.

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Trial Profile

A Phase 1 Study Assessing Safety, Tolerability, Pharmacokinetics and Physiological Response (Pain Tolerance) to Single and Multiple Ascending Doses of FZ008-145 in Healthy Subjects.

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 17 Feb 2026

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At a glance

  • Drugs FZ 008 (Primary) ; FZ 008 (Primary)
  • Indications Pain
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Guangzhou Fermion Technology

Most Recent Events

  • 12 Feb 2026 Planned number of patients changed from 168 to 190.
  • 12 Feb 2026 Planned End Date changed from 26 Dec 2025 to 1 Jun 2026.
  • 12 Feb 2026 Planned primary completion date changed from 26 Nov 2025 to 1 Apr 2026.

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