Trial Profile

A Phase 1b Open-Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Budoprutug (TNT119) in Adult Subjects With Systemic Lupus Erythematosus (SLE)

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 22 Jul 2026

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At a glance

05 May 2026 According to a Climb Bio media release, Initial B-cell data from the trial is expected in Q4 of the year.
06 Nov 2025 According to a Climb Bio media release, data from the trial are expected to provide insights into budoprutug's activity following a single intravenous dose and will help inform broader program development. Initial SLE data, including preliminary efficacy, are anticipated in the second half of 2026.
08 Jun 2025 Status changed from planning to recruiting.

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