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A Randomized, Double-blind, Placebo-controlled, Proof-of-Concept (PoC) Study to Assess the Efficacy, Safety and Tolerability of Itepekimab in Participants With Inadequately Controlled Chronic Rhinosinusitis Without Nasal Polyps

Trial Profile

A Randomized, Double-blind, Placebo-controlled, Proof-of-Concept (PoC) Study to Assess the Efficacy, Safety and Tolerability of Itepekimab in Participants With Inadequately Controlled Chronic Rhinosinusitis Without Nasal Polyps

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 16 Sep 2026

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At a glance

  • Drugs Itepekimab (Primary) ; Mometasone
  • Indications Rhinosinusitis
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Sanofi; Sanofi-Aventis Recherche & Developpement

Most Recent Events

  • 25 Aug 2026 Status changed from active, no longer recruiting to completed.
  • 05 May 2026 Planned End Date changed from 9 Feb 2027 to 18 Aug 2026.
  • 12 Mar 2026 This trial has been terminated early in Romania due to Sponsor Decision.

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