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A Phase 1/2, Open-label, Global, Multicenter, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

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Trial Profile

A Phase 1/2, Open-label, Global, Multicenter, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 03 Feb 2025

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At a glance

  • Drugs Pembrolizumab (Primary) ; PYX-201 (Primary)
  • Indications Advanced breast cancer; Cervical cancer; Gastric cancer; Head and neck cancer; HER2 negative breast cancer; Sarcoma; Solid tumours; Squamous cell cancer; Triple negative breast cancer
  • Focus Adverse reactions
  • Acronyms KEYNOTE-G17
  • Sponsors Pyxis Oncology

    • Most Recent Events

    • 28 Jan 2025 Status changed from planning to not yet recruiting.
    • 25 Nov 2024 New trial record
    • 20 Nov 2024 According to Pyxis Oncology media release, first patient expected to dose in 1Q 2025. Preliminary clinical data expected in the second half of 2025 and the first half of 2026.

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