Trial Profile

Phase I/II Study of Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Status: Not yet recruiting

Phase of Trial: Phase I/II

Latest Information Update: 16 Sep 2025

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At a glance

Drugs Azacitidine (Primary) ; Durvalumab (Primary) ; Carboplatin; Cisplatin; Gemcitabine; Paclitaxel; Pemetrexed
Indications Non-small cell lung cancer
Focus Adverse reactions; Therapeutic Use

12 Sep 2025 Planned initiation date changed from 17 Aug 2025 to 17 Sep 2025.
12 Aug 2025 Planned initiation date changed from 22 Jul 2025 to 17 Aug 2025.
17 Jul 2025 Planned initiation date changed to 22 Jul 2025.

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